I once submitted a story by email at 9:45 pm. By 10:15, not half an hour later, I had an email rejection. First off, what was some agent doing in the office or online at that hour. Second off, I stopped believing that all publishing house read each submission and treat them with the same consideratino aas every other submission. I've kept every one of my rejections (including the two that arrived in the mail months after I was already contracted to be published). They just served to show me I was a little closer to my goal.