It's exciting and unnerving to send out a manuscript, perhaps more so when you know what you're actually doing. The first time, we may think that the MS is perfect, the agent/editor will gasp and say, "This is exactly what I've been searching for," and we will be on the way to reader adulation. By the tenth or hundredth time, you've done some research and you know a few things. First, it probabl…